This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
- Series: Methods in Molecular Biology (Book 1828)
- Hardcover: 569 pages
- Publisher: Humana; 1st ed. 2018 edition (September 1, 2018)
- Language: English
- ISBN-10: 1493986503
- ISBN-13: 978-1493986507
- Product Dimensions: 7 x 1.2 x 10 inches
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