Methods in Molecular Biology Vol.1824 Rational Drug Design Methods and Protocols


This volume covers several aspects of rational drug design, such as synthesis of novel bioactive drugs; development and application of new methodologies; computational methods valuable for the establishment of new approaches in drug discovery; and the effects of physical-chemical and ADMET properties of the designed potential drugs. Chapters guide readers through amyloid deposits, Saturation Transfer Difference (STD) NMR, methods on bioguided design, the importance of lipophilicity in drug design, ADMET, FRET, structural biology, and homology modeling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
  • Series: Methods in Molecular Biology (Book 1824)
  • Hardcover: 465 pages
  • Publisher: Humana Press; 1st ed. 2018 edition (July 24, 2018)
  • Language: English
  • ISBN-10: 1493986295
  • ISBN-13: 978-1493986293
  • Product Dimensions: 7 x 1.1 x 10 inches
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